Alpha Brain Side Effects | What You MUST Know

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Curious about Alpha Brain side effects?

Then you’re in the perfect place. The reality of the situation:

Alpha Brain is one of the safer nootropics on the market.

As one of the premier over-the-counter smart drugs, the majority of users experience little to no side effects when consuming Alpha Brain.

You shouldn’t have any worries when taking this smart drug, but for individuals looking for more detailed information…

Everything you’d ever want to know about Alpha Brain side effects can be found below.

Disclaimer: The contents of are for informational and educational purposes only. We do not provide legal advice. Likewise, we do not provide medical advice, diagnosis, or treatment. Please consult your physician prior to consuming Modafinil or related nootropics. Your access to is subject to our full Disclaimer and Terms of Use.

What is Alpha Brain?

Well, that’s pretty simple. As one of the premier over-the-counter smart drugs, Alpha Brain rapidly rose to popularity after it hit the market in 2011.

Created by Onnit Labs, the nootropic is insanely popular in many circles due to high praise and endorsements from Joe Rogan, among other celebrities.

But let’s not beat around the bush here, the real reason this smart drug has found popularity is because the stuff actually works.

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Alpha Brain offers strong and useful benefits like:
  • Enhanced memory and retention
  • Increased focus
  • Improved productivity
  • …And much more!
Alpha Brain ingredients include some of the most well-known nootropics, like L-Theanine, B vitamins, Alpha-GPC, Phosphatidylserine, and Bacopa monnieri are what make it so effective. To top it all off, Alpha Brain is one of a handful of nootropics that have been scientifically proven to work [1, 2]. I’ve written a whole other article answering the question, “does Alpha Brain work?” — so check that out for more of the science. The evidence is pretty clear: Alpha Brain works. This nootropic is perfect for people new to smart drugs and looking for something a little stronger than a cup of coffee. Alpha Brain is ideal when you want to enhance the mind for 4-6+ hours.

Alpha Brain Side Effects | What You MUST Know

Even though this is one of the safer smart drugs, there’s no doubt a few minor Alpha Brain side effects may pop up from time to time.

That’s just how life goes when using nootropics. Luckily, you won’t see any serious issues with this one. And even the minor issues here only occur relatively rarely. In one study, only about 9% of people experienced any side effects, and 0% experienced severe side effects [1].

Here are seven common Alpha Brain side effects to look out for:

  • Nausea

Personally, this was one of the Alpha Brain side effects I dealt with. I had minor nausea and stomach pain when using Alpha Brain for the first time. Luckily, minor just meant one time using the restroom and everything was good. This only occurred the first time I used the nootropic. After that, I was all good. A few people experience nausea when taking Alpha Brain. But it’s never severe and tends to go away once your body adjusts to the nootropic.
  • Headaches

I didn’t experience much in the way of headaches when taking this nootropic, but certain users experience minor headache issues with Alpha Brain [1].

From a little digging, I believe this is due to not drinking enough water while on the smart drug.

When taking a number of nootropics, you may get in the zone and forget about food and water intake. When this happens, it’s easy to get dehydrated and end up with a minor headache.

Just grab a water bottle and squeeze a lime in it while taking Alpha Brain. This will keep you hydrated and is a great source of electrolytes.

  • Jaw Pain

Jain pain can be a side effect of Alpha Brain. A few users experience this issue, often when the headaches first start to kick in.

Again, I believe this comes from being in the zone and tightening your jaw as you focus on a project for hours on end.

While I haven’t experienced this symptom, most users report the pain isn’t bad and goes away quickly.

  • Body Odor

This was one Alpha Brain side effect I did notice. My body odor was slightly changed and stronger on days I take the nootropic.

While this isn’t a huge deal, you don’t want to be stinking up the coffee shop or co-working space.

As such, make sure to apply a little extra deodorant when taking Alpha Brain and you should be good to go.

  • Vivid Dreams and Nightmares

One of the more interesting side effects of Alpha Brain is the vivid dreams and nightmares that some people experience.

I never had this issue, but some users report crazy dreams and occasionally, a nightmare that wakes them from their slumber.

This is generally associated with a few of the main ingredients in Alpha Brain. Overall, this shouldn’t be a huge concern for most—unless you already have vivid dreams every night.

  • Jitters and Anxiety

With many nootropics, jitters and anxiety can pop up from time to time. This shouldn’t be a surprise since often nootropic substances are also stimulants. The stimulating effect is what makes your brain work better.

I never got anxiety from Alpha Brain, but a little restlessness can be expected for the first 15-20 minutes when the smart drug kicks in.

Overall, you needn’t worry too much about this as it goes away quickly and the work starts to flow immediately after.

At the same time, it’s good to note that those prone to anxiety should be cautious about taking any nootropics.

  • Sleeplessness

Lasy, but not least: you could experience sleeplessness when taking Alpha Brain. However, this effect should not be pronounced unless you do one thing wrong…

Take Alpha Brain at night!

Unless you want to stay up late or pull an all-nighter, try to only take Alpha Brain in the mornings or early afternoons. It has a stimulant effect, which means that it can be difficult to sleep afterward.

The drug only kicks hard for 4-6+ hours, but you don’t want to take it at 7 pm and expect to be asleep before midnight.

Is Alpha Brain Safe?

Because it’s a nootropic for beginners, lots of people wonder: is Alpha Brain safe to use?

The short answer is: yes.

The long answer is that it can depend a bit on who you ask. Some people think that the side effects listed above can be uncomfortable.

Personally, I’ve found Alpha Brain to be one of the safest smart drugs on the market. And that’s backed by research: in a study on Alpha Brain, only 9% of participants experienced alpha brain side effects and none of those were severe. 0%. The study concluded that Alpha Brain is well-tolerated [1].

Is it the best nootropic I’ve tried? No.

But I feel quite confident saying you should find many Alpha Brain side effects and there’s legit zero chance you’ll have a serious medical concern after taking this nootropic. (Although, of course, I’m no doctor.)

Most users report very few side effects on Alpha Brain, and I’ve yet to find a source where users had significant issues.

Overall, I can’t find a single course of information that states any major medical issues from Alpha Brain. No hospitalizations, no death, no overdose issues [1, 2]. Nothing.

TL:DR – Everyone reacts to things differently, but Alpha Brain is quite safe overall.

Can You Take Alpha Brain Every Day?

It’s safe… so, can you take Alpha Brain every day?

You probably could, but it’s not a great idea.

While there haven’t been any studies that I’ve found that says Alpha Brain is addictive, it’s generally the case that you don’t want to take substances every day because there’s a chance your body will get dependent on it.

That’s the same for almost every substance, including caffeine [3], nicotine [4], and so on. What happens is that the substance helps your brain out by creating some extra chemicals… but then your body eventually may develop a tolerance adapt to produce less of its own chemicals in response to long term use [5].

Again, while there’s currently no evidence of that happening with Alpha Brain, the smart bet is on taking it only occasionally. That way you’ll get the benefits and you don’t have to worry about the negative effects.

Alpha Brain Alternatives

So Alpha Brain works even if it’s not the best nootropic on the market. But what are the best nootropics on the market? What are some effective Alpha Brain alternatives?

Here’s two of the best alternatives available:

  • Modafinil

Modafinil is probably my favorite Alpha Brain alternative. It’s just super effective for what it does. If you want 10-12 hours of clear, unbridled productivity to zoom through your work, Modafinil is for you [6].

Modafinil is a prescription medication in the US and is used to treat narcolepsy [7], sleep apnea [8], shift work sleep disorder [9], and ADHD [10]. It’s been found to be super effective.

Best of all, it’s safe: studies show that there is a very low incidence of side effects and that there is a low risk of abuse [11]. That means that you’re not likely to get addicted to it.

It’s my favorite nootropic and one of the best alternatives to Alpha Brain.

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  • Mind Lab Pro

Mind Lab Pro is another of the best alternatives to Alpha Brain.

They’re actually similar in that they both are blends of a bunch of ingredients that have cognitive-enhancing properties. But in my experience Mind Lab Pro is a little stronger and lasts longer.

The other thing I like about Mind Lab Pro is that it also seems to boost my creativity.

This is a big difference: both Modafinil and Alpha Brain get me to focus and be productive, but I tend not to have as many good, novel, and creative ideas using them.

With Mind Lab Pro, I can get the work that I need done without sacrificing the quality and originality of my ideas. And it even improves your mood. Who can argue with that?

If you're looking for the #1 Modafinil alternative on the market...
That is our top recommendation.

Alpha Brain Side Effects | Verdict

Is Alpha Brain safe?

Overall, Alpha Brain is completely safe and effective. Alpha Brain ingredients include a bunch of known, well-tolerated substances.

This is NOT a dangerous smart drug.

Alpha Brain side effects will not cause you many issues, especially if dosed properly and taken in the morning after a fat-filled breakfast.

Alpha Brain is one of the safest, best beginner nootropics available.

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  1. Solomon, T. M., Leech, J., deBros, G. B., Murphy, C. A., Budson, A. E., Vassey, E. A., & Solomon, P. R. (2016). A randomized, double‐blind, placebo-controlled, parallel-group, efficacy study of alpha BRAIN® administered orally. Human Psychopharmacology: Clinical and Experimental, 31(2), 135-143.
  2. Soloman, T. M., Budson, A. E., deBros, G. B., Murphy, C. A., Vassey, E., & Soloman, P. R. (n.d.). A Proof of Concept for a Randomized, Double Blind, Placebo Controlled, Parallel Group, Efficacy Study of Alpha Brain(TM) Administered Orally [poster].
  3. Pohler, H. (2010). Caffeine intoxication and addiction. The journal for nurse practitioners, 6(1), 49-52.
  4. Stolerman, I. P., & Jarvis, M. J. (1995). The scientific case that nicotine is addictive. Psychopharmacology, 117(1), 2-10.
  5. Wikipedia (n.d.). Substance dependence.
  6. Teodorini, R. D., Rycroft, N., & Smith-Spark, J. H. (2020). The off-prescription use of modafinil: An online survey of perceived risks and benefits. PloS one, 15(2), e0227818.
  7. Bastoji, H., & Jouvet, M. (1988). Successful treatment of idiopathic hypersomnia and narcolepsy with modafinil. Progress in Neuro-psychopharmacology and Biological Psychiatry, 12(5), 695-700.
  8. Ballard, R. D. (2008). Management of patients with obstructive sleep apnea. Journal of Family Practice, 57(8), S24-S24.
  9. Greenhill, L. L., Biederman, J., Boellner, S. W., Rugino, T. A., Sangal, R. B., Earl, C. Q., … & Raffin, M. J. (2006). Modafinil: a review of its use in excessive sleepness associated with obstructive sleep apnoea/hypopnoea syndrome and shift work sleep disorder. CNS Drugs, 19, 785-803.
  10. Peñaloza, R. A., Sarkar, U., Claman, D. M., & Omachi, T. A. (2013). Trends in on-label and off-label modafinil use in a nationally representative sample. JAMA internal medicine, 173(8), 704-706.
  11. Schmitt, K. C., & Reith, M. E. (2011). The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors. PloS one, 6(10), e25790.

Table of Contents

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