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|Drug Name:||Modafinil (Provigil, Modalert, Modvigil, etc.)|
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We’ll show you not only how we buy modafinil online, but we’ll also address some of the most common concerns we hear about this nootropic, including in relation to its safety profile, benefits and legal status.
Let’s dive in!
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Overview of Modafinil
Modafinil is a potent wakefulness-promoting agent that was first approved for medical use in the United States in 1998. It’s now a prescription-only drug in most countries, including in the US, the UK, and Australia.
Doctors commonly prescribe modafinil to patients who suffer from excessive sleepiness associated with narcolepsy, a condition that causes sufferers to fall asleep at inconvenient times throughout the day.
Modafinil is also prescribed to patients who suffer from sleep-related disorders such as sleep apnea and shift work sleep disorder (SWSD) .
But the story doesn’t end there.
Modafinil is perhaps better known for its off-label cognitive enhancement applications. Over the years it has gained widespread attention as a so-called “smart drug,” or “nootropic.”
Modafinil is a powerful mind performance enhancer reported to offer impressive cognitive benefits in even otherwise healthy adults . Some of these are frequently reported to include:
- Hours of sustained focus
- Enhanced cognition
- Improved memory retention 
- Better attention span 
- Increased output and productivity
- Ability to work without feeling fatigued
We’ll take a closer look into these purported cognitive benefits of modafinil below.
But first, know that there are some potential trade-offs when taking this potent compound.
How to Use it Safely
Modafinil is sold under a variety of brand names and is typically available in 100 mg and 200 mg serving tablets.
The standard prescription dose to promote wakefulness in patients with sleep disorders is 200 mg daily, taken once a day with or without food. Whereas narcolepsy and obstructive sleep apnea patients usually take their dose in the morning, SWSD patients are typically directed to take it one hour prior to starting their shift. If you have been prescribed modafinil, simply use it as directed by your physician.
On the non-medical side of things, nootropics users report taking anywhere from 50 mg – 300 mg of modafinil per day.
As the adage goes: it’s always best to err on the side of caution. In the absence of professional guidance, first-time modafinil users are well-advised to start on a low dose and consistently monitor for potential side effects or reactions.
If no side effects are observed, then users often increase the dose and/or frequency of usage to maximize their perceived benefits, while minimizing side effects.
For more information on how nootropics users have chosen the doses that work best for them, check out our modafinil dosage guide.
Warnings and Precautions
Like every prescription drug, modafinil comes with warnings, precautions and contraindications.
There are a variety of circumstances in which modafinil use should be avoided or very closely monitored. For example, physicians often consider the following circumstances or conditions as reasons to not prescribe modafinil [5, 6]:
- Mothers who are breastfeeding their children
- Pregnancy (a few small studies have shown birth defects in newborn babies)
- Heart disease
- Suboptimal liver function
- Drug abuse/dependence
- Use of birth control (modafinil can reduce its effectiveness)
- Drug interactions with existing medications
When starting the drug, it is equally important to monitor for allergic reactions, skin rashes and blood pressure.
It’s imperative to stop using modafinil and see a physician right away if you note any mental problems like aggressive behavior, anxiety, depression, hallucinations or thoughts of suicide after taking the drug.
While modafinil has a low risk of dependence and is generally non-addictive, make sure to see a doctor if you think you may have become mentally or physically dependent on it .
It is generally advisable to avoid all other medicines, supplements, alcohol and caffeine while modafinil is still in your system.
Most users report that modafinil produces minimal side effects when taken at the standard dose of 200 mg/day or less. However, all modafinil users should look into the drug’s potential side effects and safety before taking it.
Based on a study into the use of modafinil as a wakefulness promoter for military aviators, Modafinil is well tolerated at doses of 100 mg per day . This study looked at the incidence of adverse effects among 243 members of the Republic of Singapore’s Air Force (RSAF), finding that “none of the aircrew members experienced major adverse drug events.”
In the research, the most common reported side effects of modafinil are:
- Mild headaches
- Moderate anxiety
- Dehydration (which can lead to headaches)
- Upset stomach
Fortunately, we find that these side effects may be minimized or eliminated by taking a few simple precautions, including taking modafinil in the early morning, drinking plenty of water, and making sure to follow a regular eating schedule.
Other modafinil side effects and safety concerns include :
- Dry mouth
- Chest pain
- Fast/pounding/irregular heartbeat
While this goes without saying, if you develop chest pains you must seek medical attention immediately.
In our experience, the vast majority of healthy modafinil users experience relatively mild, if any, side effects when taking the drug.
Frequently Asked Questions
What are the Benefits of Modafinil?
By now, you’re probably well aware of modafinil’s ability to change the lives of patients with sleep disorders.
But can it work the same magic as a cognitive enhancer in otherwise healthy adults?
Based on the data available — both clinical and anecdotal — the answer is a resounding “yes.”
Let’s first take a look at how the drug works.
Generally speaking, modafinil causes histamine levels in the brain to rise, causing extreme alertness in the user and preventing feelings of sleepiness or fatigue [10, 11]. Modafinil also enhances working and episodic memory by increasing the amounts of dopamine, serotonin and norepinephrine in the brain [12, 13].
A lesser-known mechanism of Modafinil is that it reduces reactivity to fear stimuli in the amygdala, the region of the brain that’s central to the modulation of anxiety . This mechanism lets the user think more clearly and work more effectively, even if they are stressed or are under a lot of pressure.
This provides great context for going into the cognitive benefits of modafinil.
In fact, research shows that modafinil has a significant effect on “mood, fatigue, and cognitive performance” in the course of sustained “sustained mental work” . Findings like these have made modafinil attractive to individuals who engage in complex intellectual labor and/or those needing to remain active and engaged for hours at a time.
Further research has indicated that the drug offers “cognitive neuroenhancement” even in “healthy non-sleep-deprived subjects” — meaning those without a sleep-wake disorder . This has been seconded by research findings that modafinil has a pronounced “effect on cognition” .
Can You Overdose on Modafinil?
Should I Be Worried About Drug Interactions?
Ordering Modafinil Online | Verdict
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