Modafinil for the Treatment of Excessive Daytime Sleepiness in Parkinson’s Disease: A Case Report

Tomas Thorne

Last Updated: February 2, 2023

Modafinil - Cocaine


We report a 59 year old woman with levodopa responsive Parkinson’s disease who developed excessive daytime sleepiness [Epworth Sleepiness Scale (ESS) score of 13]. Treatment with Modafinil 400mg daily within two weeks produced a subjective improvement in her daytime sleepiness (ESS score after treatment is 8) with no significant change in her PD motor symptomotology.


Table of Contents
    Add a header to begin generating the table of contents